Handy tip: Vitamin D deficiency causes chronic inflammation (which means aging, dementia, bad stuff)

How many people have died of a vitamin D3 deficiency in the last 20 years?

If you are deficient in Vitamin D3, you may reduce chronic inflammation just by taking this five cent supplement and getting a bit of sun. A new study finds evidence that low levels of Vitamin D are not just linked, but cause the dreaded chronic inflammation which is so tied to aging that researchers talk about inflammaging in medical papers. The term captures the diabolic systemic effects of inflammation that accelerate aging, dementia and heart disease and a whole alphabet of other conditions. But don’t wait for your CDC, NHS, or AHPRA-approved-doctor to tell you. The global anti-inflammatory drugs market was worth USD 94 billion a few years ago. Imagine what it would do to that market if everyone sorted out their vitamin D levels?

Since Covid exacerbates inflammation, and people who are obese find it very hard to get their vitamin D blood levels up, it fits that aging, inflammation, obesity and low vitamin D3 make for a bad combination with SARS-2. And if inflammation causes some cases of Long Covid, then it seems to me that vitamin D3 may help with that too.

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Wow. Vitamin D deficiency may cause 40% of respiratory deaths in older people

It’s really quite a scandal.

Missing out on the Sunshine Vitamin?

Historians will marvel that societies that were advanced enough to stream reality-tv-shows at 100 million bits per second, were also so backwards that half the population was deficient in Vitamin D — something that costs 6 cents a dose or comes free from the sun. Nearly 60% of older Germans were deficient, and the ESTHER study puts a fine point on how much that matters. Almost 10,000 people were followed for 15 years in Germany, and during that time about half the people who died of respiratory illnesses might not have died if they had enough Vitamin D.

In this German study 44% did not have adequate Vitamin D and about 1 in 6 people have levels so low they are clinically deficient.

Imagine if someone found a drug that stopped nearly half of all influenza deaths?

Right now, the Northern Hemisphere has higher levels of Vitamin D than most months which is quite likely reducing the death rates. The message needs to get out about Vitamin D before the next Northern Winter.

 

Morethan half the population is deficient.

In terms of respiratory diseases, those whose […]

Perhaps solve the other pandemic: Vitamin D deficiency — to help beat Coronavirus?

Missing out on the Sunshine Vitamin?

We’re throwing billions at Coronavirus but missing cheap wins.

After masks and soap, the next bargain to reduce the impact of coronavirus is Vitamin D supplements.

Vitamin D deficiency is so common it’s an epidemic affecting a billion people around the world. Ponder that half the population of many western nations are clinically deficient by the end of winter. Add that to a novel virus and consider that higher Vitamin D levels reduce the risk of respiratory tract infections like influenza by as much as 40%.

As Grant et al say:

“Low vitamin D status in winter permits viral epidemics.”

Vitamin D levels also correlate with lower rates of cancer, diabetes, high blood pressure, asthma, heart disease, dental caries, preeclampsia, autoimmune disease, depression, anxiety, and sleep disorders. Vitamin D influences over 200 genes. It’s so crucial, it was likely the reason northern Europeans evolved whiter skin. The lack of sunlight and the introduction of grains in diets (as opposed to eating liver and whales) meant that Europeans weren’t getting enough D from either food or sun. The selective pressure was so strong that lighter skin rapidly took over all the northern […]

One in six dementia cases might be avoided with Vitamin D

Click to enlarge | Paper

Just imagine that 17% of dementia cases could be prevented with a new drug that cost five cents, had a huge safety margin, and virtually no risk?

The study from the University of South Australia looked at data from 294,000 people in their 60s in the UK, and followed them for a median of 11 years or so. Researchers even controlled for time spent outdoors, types of physical activity, and the amount of oily fish they ate to try to cover for other benefits from these activities.

Seems to me, that if Ministers of Health were interested in actual health, they might be offering free Vitamin D tests, free supplement bottles, lessons in school and public awareness programs. They might even offer testing clinics in shopping centre car parks or free bottles at the RSL and Bowls clubs. Crazy idea right? In the world you thought you were living in, the treasurer might be chasing them down to forecast savings on public health spending ten years from now by keeping 1 in 6 out of nursing homes. Instead our Departments of Health are apparently keen to approve patented drugs with few clinical benefits […]

What if Vitamin A could stop 70% of severe cases of Covid?

For anyone who is “vitamined-out” — ponder that the most important theme is not just about personally avoiding hospitalization, it’s Where the hell are our publicly funded universities? Does the Minister for Health serve the People, or Pfizer…

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Vitamin A was allegedly once called “ “the anti-infective vitamin” — a snappy title which didn’t stick with any biochem student beyond the end of the sentence. But it’s needed for your immune system to function normally, so it seems sort of obvious to ask “what if” we don’t have enough. Could taking more prevent people catching Covid or ending up in hospital, or dead?

Vitamin A |

As always, research in prevention and prophylaxis is a wasteland in the the Modern West. No one can profit from it and indeed if everyone got enough it could harm the prospects of shareholders of Pharmaceutical firms and Hospitals. But it appears we definitely don’t want to be short of it. About three quarters of people who end up in the severe ward of Covid hospitals were deficient.

Imagine a Minister of Health who embarked on a program to raise awareness, test and give out free supplements? Lordy! It […]

It’s a Pandemic of the Vitamin D Deficient: A few dollars of D3 in hospital reduced deaths 60%

Did someone say there’s a hospitalization crisis?

There is a crisis. People are getting stuck for days extra in hospitals and even dying because of nutrient deficiencies that we could easily solve.

A new study from Istanbul shows that even if we negligently fail to correct Vitamin D deficiencies before people get sick, we can still save half of the ones who might die with a cheap vitamin, pumped in hospital for about 1/5000th of the daily cost of an ICU bed.

The mortality rate in the unsupplemented group from 2020 was 11%, but in the supplemented group in 2021 it was 5.5%. Imagine what the mortality rate might be if these people weren’t deficient in the first place?

The study shows us that there is a causal connection between low Vitamin D and more severe Covid. It also shows what a train wreck our medical systems are. For the price of a few dollars we can free up a lot of hospital beds and stop a lot of deaths, and we’ve known this might be the case since the beginning, and we’re still not doing it? The incentives are so screwed in our healthcare systems that […]

People deficient in Vitamin D are 14 times more likely to get severe Covid

How badly do our Health Ministers want to reduce Covid infections and deaths? Not much. If they were at all serious — before they hand out free vaccines, they’d hand out free Vitamin D supplements.

In a study conducted in a Galilee hospital, 26 percent of vitamin D-deficient coronavirus patients died, while among other patients the figure was at 3%. — Times of Israel

If only black lives mattered? Dark skins are so much more likely to be deficient, this is one of those absolutely easy wins for any politician, yet none of them are doing it?

Nearly half the people in the study were deficient, and half of those who were seriously deficient in Vitamin D would go on to develop a severe case. These were the people with levels below 20 ng/ml. Of all the people above that, only 10% would get a severe case. And just being “above 20ng” would still be classified as moderately deficient by many measures, yet it made such a huge difference.

It was a life and death thing — the mortality rate was 25%, fully five times higher for those who fell below the 20ng/ml bar.

The Israeli study […]

Vitamin B6 may reduce the cytokine storms of Covid

Maybe getting enough Vitamin B6 will reduce deaths

The main two things that kill people with Covid are blood clotting and an out-of-control inflammation known as a cytokine storm. A group of researchers noticed that both of these were things Vitamin B6 was known to reduce — blood clotting, and inflammation. In particular, there’s a molecule called Interleukin 6 which is a “masterplayer” signal in our immune system and — what do you know — B6 reduces it. Mice that weren’t fed enough B6 got mouse pneumonia more than mice who were fed enough. B6 is anti-inflammatory, anti- and reduces reactive oxygen species (ROS).

The Big Black hole in medical research?

I hoped this paper was report on experiments with Covid patients, but the paper and press release is essentially a literature review of many pre-covid studies and a plea for research into whether vitamin B6 might help stop the deadly cytokine storm.

The bigger, global question they don’t ask, is why despite the millions (billions) going into vaccine design and drug research, hardly anyone is studying the cheap unprofitable and obvious questions? Perhaps we need some government funded research that’s not driven by profits… oh. wait.? What happened to […]

Pandemic of incompetence? Vitamin D reduced intensive care by 80%. Ministers don’t care?

If a new drug reduced deaths by 10% it would almost get a Nobel Prize — that is, as long as it made someone rich.

A free antiviral shining down on you?

At the Hospital del Mar in Barcelona 930 people who turned up with Covid were randomly asked to take a vitamin D3 (calcifediol) treatment or a placebo. Of them, 551 were given four doses of Vitamin D3 over the next four weeks. The other 379 luckless people got the chance to be randomized controls..

The lucky ones got 20,000IU (or 20 normal vitamin D3 tablets) on day one, then 10,000 IU (ten normal tablets) on four other days in the next month. (Technically, the big dose was given was given on day one followed up with half doses on day 3, 7, 15, and 30.)

In the hapless control group as many as 80 people (21%) would go on to need Intensive Care (ICU). And 57 people of the original 379 would end up dying, or about 15%.

Of the 551 people given five dollars worth* of Vitamin D (that’s the cost online) only 30 (5%) would go on to need the ICU, and all up 36 […]

Junk study on Vitamin D shows nothing much but how bad science reporting is

The Sunlight Vitamin

UPDATED! Mea Culpa from me. The post has been corrected*. Thanks to Rob.

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More junk reporting from the Australian government broadcaster the ABC which just copies the junk science press release. Is this what we pay $1b a year for?

The Journalists missed the key factor which was blood levels of participants.

The headline says Clinical trial finds vitamin D does not ward off colds and flu but all it really shows is that in a group that already have *normal, non-deficient levels* of Vitamin D, taking big doses of Vitamin D once a month won’t will raise your blood levels — but won’t make a big difference to your risk of respiratory infections. And it only applies to people aged 60 -74.

Most participants in the study had a normal but sub-optimal Vit D levels and after five years of sporadic high doses, were raised to optimal levels at the end.

After taking 60,000 IU each month, supplementers apparently went from having 77.5 nmol/L up to 114.8 nmol/L,. To put this in perspective, normal levels of Vitamin D start at “50” and above, and there are professors who point out that there are […]

Vitamin D reduced the rate of ICU admission from 50% to 2%. Do black lives matter?

Given that people with dark skin are more likely to be deficient in Vitamin D, wouldn’t studies like these be the best way to show that black lives actually matter? Would you like training in cultural sensitivity or to avoid the intensive care unit?

A free antiviral shining down on you?

In the Castillo study in Spain, 76 patients were randomly assorted into Calciferol treatment ( 0.532 mg Vitamin D ). Of the 26 who didn’t get it, 13 were admitted to the ICU. Of the 50 who got Vitamin D doses on days 1, 3, and 7 — only one ended up in the ICU. It’s worth noting that all patients got HCQ as well, and azithromycin too.

A second study tested 500 people to find out if they were deficient and followed them to see if they caught Covid.

Why has it taken 6 months of pandemic to do these small studies?

Before the pandemic came there was already ample evidence suggesting that it mattered. Vitamin D influences over 200 genes. Its levels also correlate with lower rates of cancer, diabetes, high blood pressure, asthma, heart disease, dental caries, preeclampsia, autoimmune disease, depression, anxiety, and sleep disorders. […]

Indonesian study: Low Vitamin D patients ten times more likely to die of Coronavirus

Wow. If this is confirmed, Coronavirus is almost a disease of Vitamin D deficiency

Missing out on the Sunshine Vitamin?

Hot off the press: A new Indonesian study of 780 people with Coronavirus found that people with a Vitamin D deficiency were much more likely to die. We discussed Vitamin D at length a few weeks ago, so we already knew Vitamin D is associated with a lower rate of respiratory illness, but the results here are quite remarkable.

Of those who died most (85%) had a co-morbidity, the real surprise is that even more than that, 96% had low Vitamin D levels. Of those who survived, most people had normal Vitamin D levels. Only 7% of survivors had low or deficient Vitamin D. That is quite a split.

Vitamin D deficiency was very common among these Indonensian patients. Half of those measured did not have enough Vitamin D in their blood. Of those that did, 96% survived, and only 4% “expired”. Vitamin D looks like a good protector.

After controlling for known risk like being old, or male or having high blood pressure, a Vitamin D level described as deficient (less than 20ng/ml) was associated with a 10 […]

Dear UK, from hot Australia, your NetZero policies will kill far more people than a 40C weekday

Even the Australian ABC was telling Australians with a straight face that the extreme heat in the UK was so dangerously bad that healthy young people might die in the heat. For most Australians, it’s not summer if it doesn’t hit 40. And for people with a sauna, it’s not fun if it’s not 60 degrees. People enjoy an hour at 60C all the time without dying. We are mammals, we just need to drink. (And make sure we never forget the kids in the car).

Toby Young at the Daily Sceptic found the perfect study released last week reminding us of how deadly UK heatwaves are:

There are Eighty Times More Excess Deaths Associated With Cold Each Year than Heat

According to a recent study in the Lancet Planetary Health, between 2000 and 2019, there were an average of 65,000 excess deaths per year in England and Wales associated with cold, but fewer than 800 a year associated with heat. In other words, roughly 80 times more deaths per year are associated with cold than heat.

London School of Hygiene and Tropical Medicine

The eighty fold difference shows how serious a UK winter is, and […]

Petition the Australian TGA to consider cheap drugs as well as expensive ones!

Please share and sign. Closing tonight!

Some drugs are apparently too cheap to approve.

They want us to trust them, but if they won’t investigate cheap options, they don’t appear to have our interests at heart. Who do they serve?

Even if a long-used safe cheap drug reduced infections or deaths by 10% the cost-benefits of using it are obvious for everyone (except the companies that sell expensive competing products). The studies we have suggest one antiviral (and there are many others) could reduce infections by 86% and deaths by 50% or more. The antiviral successes against Covid in India, Mexico and Peru are there for all to see. If antivirals were being used in Sydney perhaps they could have halved the Ro (or more), slowed the spread, saved lives and businesses and shortened the lockdown?

Which brings us to the awkward questions that almost no one seems to be even asking: Why aren’t cheap low risk drugs already well tested ten times over? Why aren’t the TGA and Health Ministry urgently working to fix obvious clinical vitamin deficiencies like D3? Where is the ABC and our publicly funded institutions and our academics? Isn’t the point of publicly funded universities […]

What if Sydney could shorten the lockdown with cheap common drugs, but we didnt even try them?

How much does the Medical Swamp hate antivirals?

The news nobody wanted to hear (except perhaps Pharmaceutical giants): 29 new active cases in the NSW community.

Will NSW get desperate enough to try cheap drugs with low risks, mass production and promising results? It’s winter and the Delta variant is spreading. Contact tracing is rapidly being outpaced. The number of close contacts doubled overnight to 14,000.

What have they got to lose?

The Financial Review

NSW reported 44 new locally acquired COVID-19 cases, 29 of those were in the community while infectious and the number of close contacts has doubled from 7000 to 14,000 in the past 24 hours.

Premier Gladys Berejiklian said the lockdown was likely to be extended beyond Friday, July 16, unless there was a “dramatic turnaround” in coming days.

Antiviral hesitancy could be costing the state billions. What if an antiviral trial were offered to anyone who tested positive and their contacts, subject to medical advice (approved by their doctor)? It would be a great reason to go get tested. Got symptoms? — We may be able to help you and your family.

Some antivirals and vitamins like D3 appear […]

Dr Youtubey-Google, The Ministry of Truth, bans One America News “because HCQ”

Who knew that Youtube was your Doctor and Guardian of Medical Truth?

Youtube banned an entire news network for one week today because they said something about one of the cheapest most commonly prescribed drugs used around the world for millions of people for long term use for the last 65 years. I don’t know what OANN said, but if someone can find that story, I’ll add a link to it, not because I agree with it (though I might) but for the sake of free speech. This move by Youtube deprives OANN of income for the next week, and heavies them to change their reporting because there is a three strikes and you’re out rule. It also deprives potentially thousands of people for hearing a different point of view. Thus Youtube is even more powerful than any appointed Minister of Health — it is deciding not only what medication you should have but even what medication you might know of and potentially ask your doctor about.

YouTube temporarily suspends, demonetizes OANN

YouTube has barred One America News Network from posting new videos for a week and stripped it of its ability to make money off existing content […]

Where are the deaths? Ten reasons the first and second Covid waves look so different

In Europe the second wave is setting new records for daily cases but not for deaths so far (thankfully). So the big question is whether this will stay the same or follow the case tally up.

It’s probably not an accident that infections are spreading fast in mid October. Not only was it late summer in Europe, but the virus has been spreading mostly through 15 to 24 year old healthy young people and when Vitamin D levels were high. But as the Northern Hemisphere tracks away from the Sun, vitamin D levels are falling, temperatures are dropping, and the sterilizing rays of ultra violet grow weak. And, as the days grow colder people gather indoors too. Viral doses are rising.

The enduring scandal of the epidemic is that there are so many ways to treat this virus but they’re not expensive enough for the TGA to recommend them. ;- )

Lots more cases but not many deaths

Exhibit One: The United Kingdom

Some people have used this graph to claim the virus poses no threat. But it isn’t that simple.

UK New cases and Worldometer Deaths graph. (Click to enlarge)

Ten reasons death rates were lower in Europe’s […]

How about a nasal spray of Nanobodies, smaller faster and cheaper than antibodies?

The “Aeronabs” are on the way?

Right now there are more biomedical research teams focused on one problem than at any point in history, and they are armed. This is Biotech’s Big Moment, and here’s just another potential game changer. The time line here is short, and the ability to scale it is large. The seige of 2020 will end one way or another, and we will gain a whole set of tools to use on other viruses too.

If the virus has a key to get into our cells, this is like making millions of decoy locks that stick to the keys and thus disable them.

What if we could coat our lungs with tiny particles that work like PPE against coronavirus? The aim here is that one nasal spray a day might stop the virus getting entry into our cells. At the moment, one team have this working in the lab already. They’ve created a kind of cut down mini antibody, and at this stage it sticks like glue to the viral spikes. It still needs to be tested in humans, and might yet fall in a hole. But it’s another example of the potential contained […]

Australians wiped out the flu and avoided 50,000 other cases of sickness and disease

Lessons from Coronavirus

Lockdowns and border closures mean many diseases have been prevented

It’s peak season for flu here in Australia and there’s almost no sign of it. As Chris Gillham wrote here back in May, we know lockdowns stop viruses, because flu cases are 85% down. Now he shows that this extends to other diseases too, and Chris has used data from the National Notifiable Diseases Surveillance System to calculate that just shy of 200,000 fewer Australians contracted any of the notifiable diseases in the first seven months of 2020 compared to the first seven months of 2019.

Is some of that disease burden just the price of holiday-makers bringing back diseases from overseas each year?

No one wants to stop the planes returning to the skies, but it begs the question — do we have to accept the onslaught of winter germs every year?

The answer may lie with other things we’ve discovered in the Covid pandemic too — that sick people should stay home from work and school, and that we have a lot of anti-viral tools we can use. Perhaps it’s time that travellers considered taking preemptive anti-virals, which might improve their holidays and also reduce […]

Major report by MPs in UK found Open Border was a ‘serious mistake’

Do 10,000 extra infections matter?

JoNova — cheaper and faster than a Parliamentary Report — said two months ago that it was baffling that the UK locked everyone down, but kept flying in the virus. Now British MP’s are saying the same.

UPDATE: Given Boris Johnson suddenly changed policy on flights from Spain last week, immediately adding a mandatory quarantine, what’s the bet someone told him this report was coming?

No 10’s ‘inexplicable’ decision to lift quarantine at height of pandemic: MPs’ damning report condemns ‘serious mistake’ that allowed 10,000 infected people into the UK

David Barett, DailyMail

Delaying quarantine measures at the border was a ‘serious mistake’ that allowed 10,000 infected people into the UK accelerated the virus spread, a major report by MPs says.

The cross-party inquiry is highly critical of the Government’s ‘inexplicable’ decision to lift its initial quarantine measures in mid-March, ten days before lockdown.

Experts from the London School of Hygiene and Tropical Medicine calculated that up to 10,000 infected people, largely from Spain, France and Italy, imported the virus into the UK.

Viruses can only survive in people temporarily, so to beat a rogue chemical […]